幹細胞與及再生醫學

Stem Cells and Regenerative Medicine

幹細胞(stem Cell)具備自我更新及多向分化的能力,可以分化成為肝臟、軟骨、肌肉等組織細胞以及神經系統的胞。成體幹細胞分化可以運用在細胞療法(cell therapy)、組織工程(tissue engineering)、以及再生醫學(regenerative medicine)的研究與應用價值,未來對受傷或是病變的器官中的細胞或組織,可以與予修復或是更換,將可改善重大疾病之治療,如脊髓損傷(spinal cord injury)、肝硬化、中風(stroke)、老年癡呆症(Alzheimers disease)、惡性腫瘤、巴金森氏症(Parkinsons disease)等。

幹細胞種類

依發育期分

  • n早期/囊(胚)胞幹細胞(Early/Blastocystic Stem Cells)-卵未著床前,全功能性。
  • n胚胎/胎兒幹細胞(Embryonic / Fetal? Stem Cells)-卵著床後。
  • n臍帶/胎盤幹細胞(Umbilical Cord /Placental Stem Cells)-出生時。
  • n成熟/成人幹細胞(Mature /Adult Stem Cells)-出生後到死前,多功能性,少數種類為全功能性。

依功能分

  • n單功能幹細胞(Unipotent Stem Cells)-只能更新成單一種的成熟幹細胞.。
  • n多功能幹細胞(Multipotent Stem Cells)-可產生有限的它種功能型細胞、組織、器官。
  • 如血液幹細胞可生成紅血球、白血球及血小板。
  • n全功能幹細胞(Pluripotent Stem Cells)-可產生身體所有細胞型(胎盤除外)。當胎兒形成時他可發育
  • 成單功能或多功能型幹細胞。
  • n全潛能幹細胞(Totipotent Stem Cells)-含有全體基因訊息並主宰人體的細胞,他可發育成人體所有
  • 各種細胞及胎盤;存在於受精卵頭三至四次分裂期然後再形成全功能幹細胞。

早期>囊(胚)胞幹細胞 vs. 成熟成人幹細胞

早期/囊(胚)胞幹細胞成熟/成人幹細胞
取得的時機約在細胞分裂後第5天,在實驗室由囊胞內含物取出。較易被取得。從嬰兒出生到死亡前任何成熟的組織都可取得。
來源從試管受孕法產生的囊胞;一則是多餘的囊胞或者純粹為研究而產生的。腦、骨髓、血管、骨骼肌肉、皮膚、肝臟等,但從各種不同成熟組織可取出那些特殊型幹細胞則尚未完全明瞭。
特質屬全功能性容易在組織培養液內成長,生存期較長。屬多功能性、少數則屬全功能性。會發展成原取出的組織或器官,主要角色在維持及修補被取出幹細胞的原來組織、器官,從成熟組織較難被取出並且難在細胞培養液中生存太久。
潛在用途供給所有臨床有關的細胞種類無限的來源。但要其分化成期待型的細胞,手續則很繁雜。僅是某些特殊細胞的來源。可能被取出的幹細胞質量可疑,因日光或毒素及某些疾病可能已造成基因缺陷,而未被查出。

幹細胞潛在用途

幹細胞除取代任何人每日老化的細胞,現在已可或不久的未來將被用於治療某些疾病及傷害。

譬如:

  • 癌症
  • 脊椎損?
  • 骨關節疾病
  • 第一型糖尿病
  • 修復心臟衰竭
  • 再生牙齒、頭髮
  • 原發性免疫不全疾病
  • 神經系統疾病:帕金森病、老人癡呆症
  • 終極目標:完全防止老化甚或恢復年輕

剌激自已幹細胞修復受傷組織的方法

www.abicana.com/stem_cells.htm

  • METHODS TO STIMULATE YOUR OWN STEM CELLS TO REPAIR TISSUE DAMAGE
  • Some drugs or supplements can stimulate the stem-cells of the body to initiate or accelerate tissue repair.
    某些藥物或補充品能夠啟發或加速組織修復
  • Statins (for example the drug pravasatin) used to lower cholesterole levels also seem to stimulate the stem cells in the heart, thus stimulating the heart to repair itself.
  • Glyconutrients are special sugar types that are important for the communications between cells, and for proper rate and coordination of tissue repair. A supplement of the glyconutrients seem to stimulate stem cells to a right activity level. More about glyconutrients here.醣質營養素對於細胞間訊息的交換,組織修復的速度及協調是非常重要的。因為它可剌激幹細胞活力達到相當高的水準。
  • Ginseng seems to stimulate stem cell activity in the central nervous system and thereby helps mend nerve damage.
  • Generally you can stimulate your own stem cells to work optimally by supplying your body with all needed vitamins, minerals, glyconutrients, anti-oxydants and essential fatty acids.
  • GREEN PHYTO BASE Multiple Vitamine & mineral supplement powder:
  • Product made of organically grown herbal extracts contains all the vitamins and minerals you need in an easily absorbable organic form.
  • GENERAL VITAMINE AND MINERAL STORE: Here you will find preparations of any vitamine and mineral for your specific need.

自然產生的幹細胞 Produce Stem Cells Naturally

by Mary Rushing
(10/30/05) You can generate trillions of stem cells within one month when you take glyconutrients every day, if every new-born cell is coated with them. {1} {6} 每日使用醣質營養素,一個月內可以產生百萬平方(十兆)個幹細胞
The cost? Between $60 – $200 a month depending on your body’s health/toxic over-load, & history of nutrient deficiencies. On the other hand stem-cell transplants can cost $150,000 each, & some people receiving stem cell transplants end up with fungal/virus infections from a hospital stay. 醣質營養素每月只需美金60~200元,幹細胞移植每次則需15萬美金(約新臺幣450~500萬),有些人未出院前就因黴菌/病毒感染而失敗。
The generating of stem cells from taking glyconutrients is automatically recognized as self, pure & simple.醣質營養素促進幹細胞產生是自動製造出來,是自已的,很純淨、很簡單。
What Are Stem Cells?
Stem cells aren’t “finished” or part of a tissue or organ, but have the ability to generate into any other cell in the body. So a stem cell can become a neuron, a liver cell, a brain cell, a finger-nail cell…whatever the body needs.幹細胞不是終極產物也不是組織或器官的一部份,它有能力產生身體任何其他部位的細胞
Glyconutrients provide the ability for cells to recognize where the body needs help, to transfer the information, & to generate stem cells to repair or replace damaged cells.醣質營養素提供細胞能力去認知身體那裏需要幫忙,同時傳送資訊好讓自身生產幹細胞去修復或取代受傷的細胞
JAMA’s Report
On Feb. 19, 2003 the Journal of American Medical Ass’n {JAMA} reported that donor stem cells crossed the blood brain barrier and became neurons in the recipient’s brain.贈予者的幹細胞穿透血腦屏障,成為受贈者腦組織的神經原。
These People Took {& Take} Glyconutrients